KRAS Sequecing Assay Kit

  • Print
  • Email

Life-Daan JV KRAS Sequencing Assay Kit is a genetic test kit designed to detect the presence of seven mutations in the K-ras gene, it offers high mutation coverage of seven common mutations of codons 12 and 13.

-Help non-small cell lung cancer (NSCLC) patients for treatment with EGFR inhibitors, it can test more than 40 mutations, including insertion and deletion. These mutations are tied to efficacy for non-small cell lung cancer patients with EGFR-TKI targeted therapy.

-Aid physicians in identifying patients with metastatic colorectal cancer for treatment with Erbitux®. Erbitux® (cetuximab) is a drug that may be used to treat patients with metastatic colorectal cancer.

【Testing Procedure and Analysis】

  • Polymerase chain reaction (PCR) amplification of seven mutation sites,G12D、G12R、G12C、G12S、G12V、G13V/D, in KRAS codon12 and codon13
  • Gene sequencing with 3500Dx and 3500Dx XL Genetic Analyzer of purified products
  • Analysis to determine mutation presence or absence

【Individuals Suitable for Testing】

1)Patients with lung cancer who are being considered for treatment with EGFR targeted drugs;
2)Patients with metastatic colorectal cancer who are being considered for treatment with EGFR inhibitor;
3)Patients with cancer who are being considered for treatment with antibody therapy targeting EGFR.

Treatment Strategies For Target Therapy (FDA Approved)

KRAS Mutation Assay

 

立菲达安