The clinical symptoms of monkeypox are very similar to smallpox but a milder symptoms, usually presenting swollen lymph nodes.
Incubation Period: The incubation period of monkeypox is 3-17 days. During the incubation stage, symptoms may not appear. The illness and uncomfortableness commonly lasts 2-4 weeks and then the symptom disappear spontaneously.
Prodromal period: People with monkeypox virus infection may present early onset symptoms such as fever, headache, sore throat, and cough, most patients appear with lymph nodes.
Rash stage: The rash on skin is the most typical symptom of monkeypox. The rashes tend to concentrate on the face and extremities, they also appear on the oral mucosa, palms and soles, genitalia, conjunctiva, and cornea. The lesions progress through four phases—macular, papular, vesicular, to pustular—before scabbing over and desquamation.
It takes about 2-4 weeks from the onset to the scab falling off. After the scab falls off, it can leave erythema or pigmentation, or even a scar, which can last for several years. Once all scabs fall off, the person is no longer contagious.
WHO recommended polymerase chain reaction (PCR) to detect the monkeypox viral DNA from suspected people’s rash – skin, fluid or crusts, or biopsy, DaAn Gene’s monkeypox PCR detection kit complied with the WHO suggested diagnostic method, performing high sensitivity and accuracy.